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Pandemic Equation for Describing and Predicting COVID19 Evolution

The purpose of this work is to describe the dynamics of the COVID-19 pandemics accounting for the mitigation measures, for the introduction or removal of the quarantine, and for the effect of vaccination when and if introduced. The methods used include the derivation of the Pandemic Equation describ...

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Autor principal: Shur, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790332/
https://www.ncbi.nlm.nih.gov/pubmed/33437912
http://dx.doi.org/10.1007/s41666-020-00084-2
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author Shur, Michael
author_facet Shur, Michael
author_sort Shur, Michael
collection PubMed
description The purpose of this work is to describe the dynamics of the COVID-19 pandemics accounting for the mitigation measures, for the introduction or removal of the quarantine, and for the effect of vaccination when and if introduced. The methods used include the derivation of the Pandemic Equation describing the mitigation measures via the evolution of the growth time constant in the Pandemic Equation resulting in an asymmetric pandemic curve with a steeper rise than a decrease and mitigation measures. The Pandemic Equation predicts how the quarantine removal and business opening lead to a spike in the pandemic curve. The effective vaccination reduces the new daily infections predicted by the Pandemic Equation. The pandemic curves in many localities have similar time dependencies but shifted in time. The Pandemic Equation parameters extracted from the well advanced pandemic curves can be used for predicting the pandemic evolution in the localities, where the pandemics is still in the initial stages. Using the multiple pandemic locations for the parameter extraction allows for the uncertainty quantification in predicting the pandemic evolution using the introduced Pandemic Equation. Compared with other pandemic models our approach allows for easier parameter extraction amenable to using Artificial Intelligence models.
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spelling pubmed-77903322021-01-08 Pandemic Equation for Describing and Predicting COVID19 Evolution Shur, Michael J Healthc Inform Res Research Article The purpose of this work is to describe the dynamics of the COVID-19 pandemics accounting for the mitigation measures, for the introduction or removal of the quarantine, and for the effect of vaccination when and if introduced. The methods used include the derivation of the Pandemic Equation describing the mitigation measures via the evolution of the growth time constant in the Pandemic Equation resulting in an asymmetric pandemic curve with a steeper rise than a decrease and mitigation measures. The Pandemic Equation predicts how the quarantine removal and business opening lead to a spike in the pandemic curve. The effective vaccination reduces the new daily infections predicted by the Pandemic Equation. The pandemic curves in many localities have similar time dependencies but shifted in time. The Pandemic Equation parameters extracted from the well advanced pandemic curves can be used for predicting the pandemic evolution in the localities, where the pandemics is still in the initial stages. Using the multiple pandemic locations for the parameter extraction allows for the uncertainty quantification in predicting the pandemic evolution using the introduced Pandemic Equation. Compared with other pandemic models our approach allows for easier parameter extraction amenable to using Artificial Intelligence models. Springer International Publishing 2021-01-07 /pmc/articles/PMC7790332/ /pubmed/33437912 http://dx.doi.org/10.1007/s41666-020-00084-2 Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG part of Springer Nature 2021
spellingShingle Research Article
Shur, Michael
Pandemic Equation for Describing and Predicting COVID19 Evolution
title Pandemic Equation for Describing and Predicting COVID19 Evolution
title_full Pandemic Equation for Describing and Predicting COVID19 Evolution
title_fullStr Pandemic Equation for Describing and Predicting COVID19 Evolution
title_full_unstemmed Pandemic Equation for Describing and Predicting COVID19 Evolution
title_short Pandemic Equation for Describing and Predicting COVID19 Evolution
title_sort pandemic equation for describing and predicting covid19 evolution
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790332/
https://www.ncbi.nlm.nih.gov/pubmed/33437912
http://dx.doi.org/10.1007/s41666-020-00084-2
work_keys_str_mv AT shurmichael pandemicequationfordescribingandpredictingcovid19evolution