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Robust estimation of diagnostic rate and real incidence of COVID-19 for European policymakers
Policymakers need clear, fast assessment of the real spread of the COVID-19 epidemic in each of their respective countries. Standard measures of the situation provided by the governments include reported positive cases and total deaths. While total deaths indicate immediately that countries like Ita...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790392/ https://www.ncbi.nlm.nih.gov/pubmed/33411737 http://dx.doi.org/10.1371/journal.pone.0243701 |
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author | Català, Martí Pino, David Marchena, Miquel Palacios, Pablo Urdiales, Tomás Cardona, Pere-Joan Alonso, Sergio López-Codina, David Prats, Clara Alvarez-Lacalle, Enrique |
author_facet | Català, Martí Pino, David Marchena, Miquel Palacios, Pablo Urdiales, Tomás Cardona, Pere-Joan Alonso, Sergio López-Codina, David Prats, Clara Alvarez-Lacalle, Enrique |
author_sort | Català, Martí |
collection | PubMed |
description | Policymakers need clear, fast assessment of the real spread of the COVID-19 epidemic in each of their respective countries. Standard measures of the situation provided by the governments include reported positive cases and total deaths. While total deaths indicate immediately that countries like Italy and Spain had the worst situation as of mid-April, 2020, reported cases alone do not provide a complete picture of the situation. Different countries diagnose differently and present very distinctive reported case fatality ratios. Similar levels of reported incidence and mortality might hide a very different underlying pictures. Here we present a straightforward and robust estimation of the diagnostic rate in each European country. From that estimation we obtain a uniform, unbiased incidence of the epidemic. The method to obtain the diagnostic rate is transparent and empirical. The key assumption of the method is that the infection fatality ratio of COVID-19 in Europe is not strongly country-dependent. We show that this number is not expected to be biased due to demography nor to the way total deaths are reported. The estimation protocol is dynamic, and it has been yielding converging numbers for diagnostic rates in all European countries as from mid-April, 2020. Using this diagnostic rate, policy makers can obtain Effective Potential Growth updated every day, providing an unbiased assessment of the countries at greater risk of experiencing an uncontrolled situation. The method developed has been and will be used to track possible improvements in the diagnostic rate in European countries as the epidemic evolves. |
format | Online Article Text |
id | pubmed-7790392 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-77903922021-01-27 Robust estimation of diagnostic rate and real incidence of COVID-19 for European policymakers Català, Martí Pino, David Marchena, Miquel Palacios, Pablo Urdiales, Tomás Cardona, Pere-Joan Alonso, Sergio López-Codina, David Prats, Clara Alvarez-Lacalle, Enrique PLoS One Research Article Policymakers need clear, fast assessment of the real spread of the COVID-19 epidemic in each of their respective countries. Standard measures of the situation provided by the governments include reported positive cases and total deaths. While total deaths indicate immediately that countries like Italy and Spain had the worst situation as of mid-April, 2020, reported cases alone do not provide a complete picture of the situation. Different countries diagnose differently and present very distinctive reported case fatality ratios. Similar levels of reported incidence and mortality might hide a very different underlying pictures. Here we present a straightforward and robust estimation of the diagnostic rate in each European country. From that estimation we obtain a uniform, unbiased incidence of the epidemic. The method to obtain the diagnostic rate is transparent and empirical. The key assumption of the method is that the infection fatality ratio of COVID-19 in Europe is not strongly country-dependent. We show that this number is not expected to be biased due to demography nor to the way total deaths are reported. The estimation protocol is dynamic, and it has been yielding converging numbers for diagnostic rates in all European countries as from mid-April, 2020. Using this diagnostic rate, policy makers can obtain Effective Potential Growth updated every day, providing an unbiased assessment of the countries at greater risk of experiencing an uncontrolled situation. The method developed has been and will be used to track possible improvements in the diagnostic rate in European countries as the epidemic evolves. Public Library of Science 2021-01-07 /pmc/articles/PMC7790392/ /pubmed/33411737 http://dx.doi.org/10.1371/journal.pone.0243701 Text en © 2021 Català et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Català, Martí Pino, David Marchena, Miquel Palacios, Pablo Urdiales, Tomás Cardona, Pere-Joan Alonso, Sergio López-Codina, David Prats, Clara Alvarez-Lacalle, Enrique Robust estimation of diagnostic rate and real incidence of COVID-19 for European policymakers |
title | Robust estimation of diagnostic rate and real incidence of COVID-19 for European policymakers |
title_full | Robust estimation of diagnostic rate and real incidence of COVID-19 for European policymakers |
title_fullStr | Robust estimation of diagnostic rate and real incidence of COVID-19 for European policymakers |
title_full_unstemmed | Robust estimation of diagnostic rate and real incidence of COVID-19 for European policymakers |
title_short | Robust estimation of diagnostic rate and real incidence of COVID-19 for European policymakers |
title_sort | robust estimation of diagnostic rate and real incidence of covid-19 for european policymakers |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790392/ https://www.ncbi.nlm.nih.gov/pubmed/33411737 http://dx.doi.org/10.1371/journal.pone.0243701 |
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