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Interplay between UNG and AID governs intratumoral heterogeneity in mature B cell lymphoma
Most B cell lymphomas originate from B cells that have germinal center (GC) experience and bear chromosome translocations and numerous point mutations. GC B cells remodel their immunoglobulin (Ig) genes by somatic hypermutation (SHM) and class switch recombination (CSR) in their Ig genes. Activation...
Autores principales: | Delgado, Pilar, Álvarez-Prado, Ángel F., Marina-Zárate, Ester, Sernandez, Isora V., Mur, Sonia M., de la Barrera, Jorge, Sanchez-Cabo, Fátima, Cañamero, Marta, de Molina, Antonio, Belver, Laura, de Yébenes, Virginia G., Ramiro, Almudena R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790409/ https://www.ncbi.nlm.nih.gov/pubmed/33362210 http://dx.doi.org/10.1371/journal.pgen.1008960 |
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