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Multi-scale modeling of macrophage—T cell interactions within the tumor microenvironment

Within the tumor microenvironment, macrophages exist in an immunosuppressive state, preventing T cells from eliminating the tumor. Due to this, research is focusing on immunotherapies that specifically target macrophages in order to reduce their immunosuppressive capabilities and promote T cell func...

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Detalles Bibliográficos
Autores principales: Cess, Colin G., Finley, Stacey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790427/
https://www.ncbi.nlm.nih.gov/pubmed/33362239
http://dx.doi.org/10.1371/journal.pcbi.1008519