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DOCK8 deficiency diminishes thymic T‐regulatory cell development but not thymic deletion
OBJECTIVE: To define the effect of DOCK8 deficiency on thymic tolerance in mice. METHODS: Thymocytes from wild‐type (Dock8(+/+)) and DOCK8‐deficient (Dock8(pri/pri)) mice were examined by flow cytometry. Some mice had transgenic expression of the BCL2 anti‐apoptotic protein in haemopoietic cells. So...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790591/ https://www.ncbi.nlm.nih.gov/pubmed/33437483 http://dx.doi.org/10.1002/cti2.1236 |