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Machine learning applications in drug development

Due to the huge amount of biological and medical data available today, along with well-established machine learning algorithms, the design of largely automated drug development pipelines can now be envisioned. These pipelines may guide, or speed up, drug discovery; provide a better understanding of...

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Detalles Bibliográficos
Autores principales: Réda, Clémence, Kaufmann, Emilie, Delahaye-Duriez, Andrée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790737/
https://www.ncbi.nlm.nih.gov/pubmed/33489002
http://dx.doi.org/10.1016/j.csbj.2019.12.006
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author Réda, Clémence
Kaufmann, Emilie
Delahaye-Duriez, Andrée
author_facet Réda, Clémence
Kaufmann, Emilie
Delahaye-Duriez, Andrée
author_sort Réda, Clémence
collection PubMed
description Due to the huge amount of biological and medical data available today, along with well-established machine learning algorithms, the design of largely automated drug development pipelines can now be envisioned. These pipelines may guide, or speed up, drug discovery; provide a better understanding of diseases and associated biological phenomena; help planning preclinical wet-lab experiments, and even future clinical trials. This automation of the drug development process might be key to the current issue of low productivity rate that pharmaceutical companies currently face. In this survey, we will particularly focus on two classes of methods: sequential learning and recommender systems, which are active biomedical fields of research.
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spelling pubmed-77907372021-01-22 Machine learning applications in drug development Réda, Clémence Kaufmann, Emilie Delahaye-Duriez, Andrée Comput Struct Biotechnol J Short Survey Due to the huge amount of biological and medical data available today, along with well-established machine learning algorithms, the design of largely automated drug development pipelines can now be envisioned. These pipelines may guide, or speed up, drug discovery; provide a better understanding of diseases and associated biological phenomena; help planning preclinical wet-lab experiments, and even future clinical trials. This automation of the drug development process might be key to the current issue of low productivity rate that pharmaceutical companies currently face. In this survey, we will particularly focus on two classes of methods: sequential learning and recommender systems, which are active biomedical fields of research. Research Network of Computational and Structural Biotechnology 2019-12-26 /pmc/articles/PMC7790737/ /pubmed/33489002 http://dx.doi.org/10.1016/j.csbj.2019.12.006 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Short Survey
Réda, Clémence
Kaufmann, Emilie
Delahaye-Duriez, Andrée
Machine learning applications in drug development
title Machine learning applications in drug development
title_full Machine learning applications in drug development
title_fullStr Machine learning applications in drug development
title_full_unstemmed Machine learning applications in drug development
title_short Machine learning applications in drug development
title_sort machine learning applications in drug development
topic Short Survey
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790737/
https://www.ncbi.nlm.nih.gov/pubmed/33489002
http://dx.doi.org/10.1016/j.csbj.2019.12.006
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