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Machine learning applications in drug development
Due to the huge amount of biological and medical data available today, along with well-established machine learning algorithms, the design of largely automated drug development pipelines can now be envisioned. These pipelines may guide, or speed up, drug discovery; provide a better understanding of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790737/ https://www.ncbi.nlm.nih.gov/pubmed/33489002 http://dx.doi.org/10.1016/j.csbj.2019.12.006 |
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author | Réda, Clémence Kaufmann, Emilie Delahaye-Duriez, Andrée |
author_facet | Réda, Clémence Kaufmann, Emilie Delahaye-Duriez, Andrée |
author_sort | Réda, Clémence |
collection | PubMed |
description | Due to the huge amount of biological and medical data available today, along with well-established machine learning algorithms, the design of largely automated drug development pipelines can now be envisioned. These pipelines may guide, or speed up, drug discovery; provide a better understanding of diseases and associated biological phenomena; help planning preclinical wet-lab experiments, and even future clinical trials. This automation of the drug development process might be key to the current issue of low productivity rate that pharmaceutical companies currently face. In this survey, we will particularly focus on two classes of methods: sequential learning and recommender systems, which are active biomedical fields of research. |
format | Online Article Text |
id | pubmed-7790737 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Research Network of Computational and Structural Biotechnology |
record_format | MEDLINE/PubMed |
spelling | pubmed-77907372021-01-22 Machine learning applications in drug development Réda, Clémence Kaufmann, Emilie Delahaye-Duriez, Andrée Comput Struct Biotechnol J Short Survey Due to the huge amount of biological and medical data available today, along with well-established machine learning algorithms, the design of largely automated drug development pipelines can now be envisioned. These pipelines may guide, or speed up, drug discovery; provide a better understanding of diseases and associated biological phenomena; help planning preclinical wet-lab experiments, and even future clinical trials. This automation of the drug development process might be key to the current issue of low productivity rate that pharmaceutical companies currently face. In this survey, we will particularly focus on two classes of methods: sequential learning and recommender systems, which are active biomedical fields of research. Research Network of Computational and Structural Biotechnology 2019-12-26 /pmc/articles/PMC7790737/ /pubmed/33489002 http://dx.doi.org/10.1016/j.csbj.2019.12.006 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Short Survey Réda, Clémence Kaufmann, Emilie Delahaye-Duriez, Andrée Machine learning applications in drug development |
title | Machine learning applications in drug development |
title_full | Machine learning applications in drug development |
title_fullStr | Machine learning applications in drug development |
title_full_unstemmed | Machine learning applications in drug development |
title_short | Machine learning applications in drug development |
title_sort | machine learning applications in drug development |
topic | Short Survey |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790737/ https://www.ncbi.nlm.nih.gov/pubmed/33489002 http://dx.doi.org/10.1016/j.csbj.2019.12.006 |
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