HDAC6/HNF4α loop mediated by miR-1 promotes bile acids-induced gastric intestinal metaplasia

BACKGROUND: Gastric intestinal metaplasia (IM) is considered a precancerous lesion, and bile acids (BA) play a critical role in the induction of IM. Ectopic expression of HNF4α was observed in a BA-induced IM cell model. However, the mechanisms underlying the upregulation of the protein in IM cells...

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Detalles Bibliográficos
Autores principales: Wang, Na, Chen, Min, Ni, Zhen, Li, Ting, Zeng, Jiaoxia, Lu, Guofang, Wang, Jiaojiao, Zhang, Jian, Wu, Siran, Shi, Yongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790803/
https://www.ncbi.nlm.nih.gov/pubmed/32705446
http://dx.doi.org/10.1007/s10120-020-01108-x

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