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Alcohol use disorder causes global changes in splicing in the human brain

Alcohol use disorder (AUD) is a widespread disease leading to the deterioration of cognitive and other functions. Mechanisms by which alcohol affects the brain are not fully elucidated. Splicing constitutes a nuclear process of RNA maturation, which results in the formation of the transcriptome. We...

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Detalles Bibliográficos
Autores principales: Van Booven, Derek, Mengying Li, Sunil Rao, J., Blokhin, Ilya O., Dayne Mayfield, R., Barbier, Estelle, Heilig, Markus, Wahlestedt, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790816/
https://www.ncbi.nlm.nih.gov/pubmed/33414398
http://dx.doi.org/10.1038/s41398-020-01163-z