TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy

Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents, which is characterized by dysfunctional autophagy and poor differentiation. Our recent studies have suggested that the tripartite motif containing-21 (TRIM21) plays a crucial role in regulating OS cell sen...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Huan-Tian, Zeng, Qingzhong, Wu, Baomeng, Lu, Junlei, Tong, Kui-Leung, Lin, Jiebin, Liu, Qiu-Yu, Xu, Lipei, Yang, Jie, Liu, Xiaohui, Liu, Wanting, Zhang, Yun-Fang, Lian, Qionghua, Liu, Langxia, Gao, Xuejuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790825/
https://www.ncbi.nlm.nih.gov/pubmed/33414451
http://dx.doi.org/10.1038/s41419-020-03364-2

Ejemplares similares

Ejemplares similares