Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa

OBJECTIVE: Patients with Lynch syndrome (LS) are at markedly increased risk for colorectal cancer. It is being increasingly recognised that the immune system plays an essential role in LS tumour development, thus making an ideal target for cancer prevention. Our objective was to evaluate the safety,...

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Detalles Bibliográficos
Autores principales: Reyes-Uribe, Laura, Wu, Wenhui, Gelincik, Ozkan, Bommi, Prashant V, Francisco-Cruz, Alejandro, Solis, Luisa M, Lynch, Patrick M, Lim, Ramona, Stoffel, Elena M, Kanth, Priyanka, Samadder, N Jewel, Mork, Maureen E, Taggart, Melissa W, Milne, Ginger L, Marnett, Lawrence J, Vornik, Lana, Liu, Diane D, Revuelta, Maria, Chang, Kyle, You, Y Nancy, Kopelovich, Levy, Wistuba, Ignacio I, Lee, J Jack, Sei, Shizuko, Shoemaker, Robert H, Szabo, Eva, Richmond, Ellen, Umar, Asad, Perloff, Marjorie, Brown, Powel H, Lipkin, Steven M, Vilar, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Colon
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790993/
https://www.ncbi.nlm.nih.gov/pubmed/32641470
http://dx.doi.org/10.1136/gutjnl-2020-320946

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