Targeting Complement C5a Receptor 1 for the Treatment of Immunosuppression in Sepsis

Complement factor C5a was originally identified as a powerful promoter of inflammation through activation of the C5a receptor 1 (C5ar1). Recent evidence suggests involvement of C5a not only in pro- but also in anti-inflammatory signaling. The present study aims to unveil the role of C5ar1 as potenti...

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Detalles Bibliográficos
Autores principales: Sommerfeld, Oliver, Medyukhina, Anna, Neugebauer, Sophie, Ghait, Mohamed, Ulferts, Svenja, Lupp, Amelie, König, Rainer, Wetzker, Reinhard, Schulz, Stefan, Figge, Marc Thilo, Bauer, Michael, Press, Adrian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791006/
https://www.ncbi.nlm.nih.gov/pubmed/32966769
http://dx.doi.org/10.1016/j.ymthe.2020.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791006/
https://www.ncbi.nlm.nih.gov/pubmed/32966769
http://dx.doi.org/10.1016/j.ymthe.2020.09.008

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