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METTL14-regulated PI3K/Akt signaling pathway via PTEN affects HDAC5-mediated epithelial–mesenchymal transition of renal tubular cells in diabetic kidney disease

Histone deacetylase 5 (HDAC5) belongs to class II HDAC subfamily and is reported to be increased in the kidneys of diabetic patients and animals. However, little is known about its function and the exact mechanism in diabetic kidney disease (DKD). Here, we found that HDAC5 was located in renal glome...

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Detalles Bibliográficos
Autores principales: Xu, Zhaoxia, Jia, Keqi, Wang, Hui, Gao, Feng, Zhao, Song, Li, Fan, Hao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791055/
https://www.ncbi.nlm.nih.gov/pubmed/33414476
http://dx.doi.org/10.1038/s41419-020-03312-0

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