Autophagy impairment as a key feature for acetaminophen-induced ototoxicity

Macroautophagy/autophagy is a highly conserved self-digestion pathway that plays an important role in cytoprotection under stress conditions. Autophagy is involved in hepatotoxicity induced by acetaminophen (APAP) in experimental animals and in humans. APAP also causes ototoxicity. However, the role...

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Detalles Bibliográficos
Autores principales: Zhao, Tong, Zheng, Tihua, Yu, Huining, Hu, Bo Hua, Hu, Bing, Ma, Peng, Yang, Ying, Yang, Naidi, Hu, Juan, Cao, Tongtao, Chen, Gang, Yan, Bin, Peshoff, Melina, Hatzoglou, Maria, Geng, Ruishuang, Li, Bo, Zheng, Qing Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791066/
https://www.ncbi.nlm.nih.gov/pubmed/33414397
http://dx.doi.org/10.1038/s41419-020-03328-6

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