Cell-cycle arrest and senescence in TP53-wild type renal carcinoma by enhancer RNA-P53-bound enhancer regions 2 (p53BER2) in a p53-dependent pathway

TP53 is a classic tumor suppressor, but its role in kidney cancer remains unclear. In our study, we tried to explain the role of p53 in kidney cancer through the p53-related enhancer RNA pathway. Functional experiments were used to explore whether P53-bound enhancer regions 2 (p53BER2) has a role in...

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Detalles Bibliográficos
Autores principales: Xie, Haibiao, Ma, Kaifang, Zhang, Kenan, Zhou, Jingcheng, Li, Lei, Yang, Wuping, Gong, Yanqing, Cai, Lin, Gong, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791070/
https://www.ncbi.nlm.nih.gov/pubmed/33414393
http://dx.doi.org/10.1038/s41419-020-03229-8

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