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Loss of FOXC1 contributes to the corneal epithelial fate switch and pathogenesis

Forkhead box C1 (FOXC1) is required for neural crest and ocular development, and mutations in FOXC1 lead to inherited Axenfeld–Rieger syndrome. Here, we find that FOXC1 and paired box 6 (PAX6) are co-expressed in the human limbus and central corneal epithelium. Deficiency of FOXC1 and alternation in...

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Detalles Bibliográficos
Autores principales:	Li, Mingsen, Zhu, Liqiong, Liu, Jiafeng, Huang, Huaxing, Guo, Huizhen, Wang, Li, Li, Lingyu, Gu, Sijie, Tan, Jieying, Zhong, Jing, Wang, Bowen, Mao, Zhen, Fan, Yong, Liu, Chunqiao, Yuan, Jin, Ouyang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791103/ https://www.ncbi.nlm.nih.gov/pubmed/33414365 http://dx.doi.org/10.1038/s41392-020-00378-2

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