KDM6B is an androgen regulated gene and plays oncogenic roles by demethylating H3K27me3 at cyclin D1 promoter in prostate cancer

Lysine (K)-specific demethylase 6B (KDM6B), a stress-inducible H3K27me3 demethylase, plays oncogenic or antitumoral roles in malignant tumors depending on the type of tumor cell. However, how this histone modifier affects the progression of prostate cancer (PCa) is still unknown. Here we analyzed se...

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Detalles Bibliográficos
Autores principales: Cao, Zhi, Shi, Xiaolei, Tian, Feng, Fang, Yu, Wu, Jason Boyang, Mrdenovic, Stefan, Nian, Xinwen, Ji, Jin, Xu, Huan, Kong, Chen, Xu, Yalong, Chen, Xi, Huang, Yuhua, Wei, Xuedong, Yu, Yongwei, Yang, Bo, Chung, Leland W. K., Wang, Fubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791132/
https://www.ncbi.nlm.nih.gov/pubmed/33414463
http://dx.doi.org/10.1038/s41419-020-03354-4

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