Cargando…

Long noncoding RNA LINC00941 promotes pancreatic cancer progression by competitively binding miR-335-5p to regulate ROCK1-mediated LIMK1/Cofilin-1 signaling

An accumulation of evidence indicates that long noncoding RNAs are involved in the tumorigenesis and progression of pancreatic cancer (PC). In this study, we investigated the functions and molecular mechanism of action of LINC00941 in PC. Quantitative PCR was used to examine the expression of LINC00...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jie, He, Zhiwei, Xu, Jian, Chen, Peng, Jiang, Jianxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791140/ https://www.ncbi.nlm.nih.gov/pubmed/33414429 http://dx.doi.org/10.1038/s41419-020-03316-w

Ejemplares similares

LINC00941 promotes glycolysis in pancreatic cancer by modulating the Hippo pathway
por: Xu, Ming, et al.
Publicado: (2021)

Diallyl disulfide induces downregulation and inactivation of cofilin 1 differentiation via the Rac1/ROCK1/LIMK1 pathway in leukemia cells
por: Ling, Hui, et al.
Publicado: (2020)

DANCR promotes HCC progression and regulates EMT by sponging miR‐27a‐3p via ROCK1/LIMK1/COFILIN1 pathway
por: Guo, Dan, et al.
Publicado: (2019)

LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2
por: Wang, Jie, et al.
Publicado: (2022)

A Haspin-ARHGAP11A axis regulates epithelial morphogenesis through Rho-ROCK dependent modulation of LIMK1-Cofilin
por: Quadri, Roberto, et al.
Publicado: (2023)

Downregulation of LIMK1–ADF/cofilin by DADS inhibits the migration and invasion of colon cancer
por: Su, Jian, et al.
Publicado: (2017)

Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization
por: Liu, An, et al.
Publicado: (2016)

Lipin1 Is Involved in the Pathogenesis of Diabetic Encephalopathy through the PKD/Limk/Cofilin Signaling Pathway
por: Xie, Min, et al.
Publicado: (2020)

Dichotomous effects of the cofilin kinase LIMK1 on the early steps of HIV-1 infection of CD4 T cells
por: Vorster, Paul J, et al.
Publicado: (2009)

ZNRD1-AS1 Promotes Nasopharyngeal Carcinoma Cell Invasion and Metastasis by Regulating the miR-335–ROCK1 Axis
por: Wang, Qiang, et al.
Publicado: (2020)

ROCK1 and LIMK2 Interact in Spread but Not Blebbing Cancer Cells
por: Shea, Kerry F., et al.
Publicado: (2008)

Cofilin-1, LIMK1 and SSH1 are differentially expressed in locally advanced colorectal cancer and according to consensus molecular subtypes
por: Sousa-Squiavinato, Annie Cristhine Moraes, et al.
Publicado: (2021)

BDNF Induced Translation of Limk1 in Developing Neurons Regulates Dendrite Growth by Fine-Tuning Cofilin1 Activity
por: Ravindran, Sreenath, et al.
Publicado: (2019)

Effects of PAK4/LIMK1/Cofilin‐1 signaling pathway on proliferation, invasion, and migration of human osteosarcoma cells
por: Li, Zhi‐Feng, et al.
Publicado: (2020)

LINC01087 is Highly Expressed in Breast Cancer and Regulates the Malignant Behavior of Cancer Cells Through miR-335-5p/Rock1
por: She, Ji-Kai, et al.
Publicado: (2020)

Long noncoding RNA DANCR, working as a competitive endogenous RNA, promotes ROCK1-mediated proliferation and metastasis via decoying of miR-335-5p and miR-1972 in osteosarcoma
por: Wang, Yong, et al.
Publicado: (2018)

Expression changes of serum LINC00941 and LINC00514 in HBV infection‐related liver diseases and their potential application values
por: Chen, Juanjuan, et al.
Publicado: (2021)

Long noncoding RNA LINC00518 contributes to proliferation and metastasis in lung adenocarcinoma via the miR-335-3p/CTHRC1 Axis
por: Shen, Ruoyi, et al.
Publicado: (2022)

Reciprocal regulation of LINC00941 and SOX2 promotes progression of esophageal squamous cell carcinoma
por: Lu, Jun-Tao, et al.
Publicado: (2023)

DEP Domain-Containing Protein 1B (DEPDC1B) Promotes Migration and Invasion in Pancreatic Cancer Through the Rac1/PAK1-LIMK1-Cofilin1 Signaling Pathway
por: Zhang, Shan, et al.
Publicado: (2020)

Novel lncRNA LINC00941 Promotes Proliferation and Invasion of Colon Cancer Through Activation of MYC
por: Chang, Lin, et al.
Publicado: (2021)

SphK2/S1P Promotes Metastasis of Triple-Negative Breast Cancer Through the PAK1/LIMK1/Cofilin1 Signaling Pathway
por: Shi, Weiwei, et al.
Publicado: (2021)

The Wdr1-LIMK-Cofilin Axis Controls B Cell Antigen Receptor-Induced Actin Remodeling and Signaling at the Immune Synapse
por: Bolger-Munro, Madison, et al.
Publicado: (2021)

Pak1/LIMK1/Cofilin Pathway Contributes to Tumor Migration and Invasion in Human Non-Small Cell Lung Carcinomas and Cell Lines
por: Jang, Inseok, et al.
Publicado: (2012)

Linc00941 regulates esophageal squamous cell carcinoma via functioning as a competing endogenous RNA for miR-877-3p to modulate PMEPA1 expression
por: Zhang, Yan, et al.
Publicado: (2021)

LINC00941 Promotes Progression of Non-Small Cell Lung Cancer by Sponging miR-877-3p to Regulate VEGFA Expression
por: Ren, Min-Huan, et al.
Publicado: (2021)

METTL14 Facilitates the Metastasis of Pancreatic Carcinoma by Stabilizing LINC00941 in an m6A-IGF2BP2-Dependent Manner
por: Lu, Jiawei, et al.
Publicado: (2023)

Long Non-coding RNA LINC00941 as a Potential Biomarker Promotes the Proliferation and Metastasis of Gastric Cancer
por: Liu, Haiming, et al.
Publicado: (2019)

CAPRIN2 upregulation by LINC00941 promotes nasopharyngeal carcinoma ferroptosis resistance and metastatic colonization through HMGCR
por: Qiu, Lin, et al.
Publicado: (2022)

LMO3 promotes proliferation and metastasis of papillary thyroid carcinoma cells by regulating LIMK1-mediated cofilin and the β-catenin pathway
por: Ling, Zeyi, et al.
Publicado: (2022)

Endoglin Is an Endothelial Housekeeper against Inflammation: Insight in ECFC-Related Permeability through LIMK/Cofilin Pathway
por: Rossi, Elisa, et al.
Publicado: (2021)

miR-137–LAPTM4B regulates cytoskeleton organization and cancer metastasis via the RhoA-LIMK-Cofilin pathway in osteosarcoma
por: Yan, Ruyu, et al.
Publicado: (2023)

MED12 exerts an emerging role in actin-mediated cytokinesis via LIMK2/cofilin pathway in NSCLC
por: Xu, Meng, et al.
Publicado: (2019)

Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function
por: Fang, Qiaojun, et al.
Publicado: (2019)

miR-335 Acts as a Tumor Suppressor and Enhances Ionizing Radiation-Induced Tumor Regression by Targeting ROCK1
por: Cheng, Yanfeng, et al.
Publicado: (2020)

ATF3 -activated accelerating effect of LINC00941/lncIAPF on fibroblast-to-myofibroblast differentiation by blocking autophagy depending on ELAVL1/HuR in pulmonary fibrosis
por: Zhang, Jinjin, et al.
Publicado: (2022)

IP-10 Promotes Latent HIV Infection in Resting Memory CD4(+) T Cells via LIMK-Cofilin Pathway
por: Wang, Zhuo, et al.
Publicado: (2021)

Corrigendum: miR-335 Acts as a Tumor Suppressor and Enhances Ionizing Radiation-Induced Tumor Regression by Targeting ROCK1
por: Cheng, Yanfeng, et al.
Publicado: (2021)

Long noncoding RNA LINC00346 promotes glioma cell migration, invasion and proliferation by up‐regulating ROCK1
por: Chen, Xin, et al.
Publicado: (2020)

MiR-20a Is Upregulated in Anaplastic Thyroid Cancer and Targets LIMK1
por: Xiong, Yin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_me92b6nqjl0ihafcu301e4riif