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The calcium channel TRPV6 is a novel regulator of RANKL‐induced osteoclastic differentiation and bone absorption activity through the IGF–PI3K–AKT pathway

OBJECTIVES: Calcium ion signals are important for osteoclast differentiation. Transient receptor potential vanilloid 6 (TRPV6) is a regulator of bone homeostasis. However, it was unclear whether TRPV6 was involved in osteoclast formation. Therefore, the aim of this study was to evaluate the role of...

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Detalles Bibliográficos
Autores principales: Ma, Jun, Zhu, Lei, Zhou, Zhibin, Song, Tengfei, Yang, Lei, Yan, Xu, chen, Aimin, Ye, Tian Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791174/
https://www.ncbi.nlm.nih.gov/pubmed/33159483
http://dx.doi.org/10.1111/cpr.12955