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Metformin inhibits inflammation and bone destruction in collagen-induced arthritis in rats

BACKGROUND: Metformin (MF) is a widely used biguanide oral hypoglycemic agent, which has obvious anti-inflammatory and immunomodulatory effects. However, the mechanism of MF on rheumatoid arthritis (RA) remains uncertain. In this study, we investigated the therapeutic effects of MF on collagen-induc...

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Detalles Bibliográficos
Autores principales: Fan, Kai-Jian, Wu, Jing, Wang, Qi-Shan, Xu, Bing-Xin, Zhao, Fu-Tao, Wang, Ting-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791269/
https://www.ncbi.nlm.nih.gov/pubmed/33437764
http://dx.doi.org/10.21037/atm-20-3042

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