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ADAM10 is involved in the oncogenic process and chemo-resistance of triple-negative breast cancer via regulating Notch1 signaling pathway, CD44 and PrPc

BACKGROUND: Triple-negative breast cancer (TNBC) is the most challenging breast cancer subtype to treat, because it is so aggressive with shorter survival. Chemotherapy remains the standard treatment due to the lack of specific and effective molecular targets. The aim of the present study is to inve...

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Detalles Bibliográficos
Autores principales: Cheng, Yuanyuan, Lin, Lishuang, Li, Xiaoyan, Lu, Aiqi, Hou, Chenjian, Wu, Qian, Hu, Xiaomu, Zhou, Zhongwen, Chen, Zhongqing, Tang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791678/
https://www.ncbi.nlm.nih.gov/pubmed/33413403
http://dx.doi.org/10.1186/s12935-020-01727-5