Improved production of germacrene A, a direct precursor of ß-elemene, in engineered Saccharomyces cerevisiae by expressing a cyanobacterial germacrene A synthase

BACKGROUND: The sesquiterpene germacrene A is a direct precursor of ß-elemene that is a major component of the Chinese medicinal herb Curcuma wenyujin with prominent antitumor activity. The microbial platform for germacrene A production was previously established in Saccharomyces cerevisiae using th...

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Detalles Bibliográficos
Autores principales: Zhang, Weixin, Guo, Junqi, Wang, Zheng, Li, Yanwei, Meng, Xiangfeng, Shen, Yu, Liu, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791714/
https://www.ncbi.nlm.nih.gov/pubmed/33413372
http://dx.doi.org/10.1186/s12934-020-01500-3

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