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Case report: necrotizing enterocolitis with a transverse colonic perforation in a 2-day old term neonate and literature review

BACKGROUND: Necrotizing enterocolitis (NEC), while classically discussed in preterm and low birth weight neonates, also occurs in the term infant and accounts for 10% of all NEC cases. Despite there being fewer reported cases of NEC in term infants, these presentations demonstrate differences in the...

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Autores principales: Hudson, Jo-Anna, Byrns, Simon, Nizalik, Elizabeth, Ferretti, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791759/
https://www.ncbi.nlm.nih.gov/pubmed/33413665
http://dx.doi.org/10.1186/s40748-020-00124-0
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author Hudson, Jo-Anna
Byrns, Simon
Nizalik, Elizabeth
Ferretti, Emanuela
author_facet Hudson, Jo-Anna
Byrns, Simon
Nizalik, Elizabeth
Ferretti, Emanuela
author_sort Hudson, Jo-Anna
collection PubMed
description BACKGROUND: Necrotizing enterocolitis (NEC), while classically discussed in preterm and low birth weight neonates, also occurs in the term infant and accounts for 10% of all NEC cases. Despite there being fewer reported cases of NEC in term infants, these presentations demonstrate differences in the onset, severity and risk factors from the classic presentation observed in premature infants. We present a novel case of term NEC that contravenes the reported literature making departures from clinical presentation, risk factors and location of perforation in an otherwise healthy term two-day old infant born after an uncomplicated pregnancy who presented with hematochezia. CASE PRESENTATION: A healthy term baby born after an uneventful pregnancy presented with bloody stool at 2 days of life who was otherwise well. Investigations revealed pneumoperitoneum from a large proximal transverse colonic perforation secondary to NEC. No typical risk factors for NEC were found. CONCLUSION: Given the life-threatening potential of an unrecognized perforation we recommend the inclusion of NEC on the differential for neonatal hematochezia.
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spelling pubmed-77917592021-01-11 Case report: necrotizing enterocolitis with a transverse colonic perforation in a 2-day old term neonate and literature review Hudson, Jo-Anna Byrns, Simon Nizalik, Elizabeth Ferretti, Emanuela Matern Health Neonatol Perinatol Case Report BACKGROUND: Necrotizing enterocolitis (NEC), while classically discussed in preterm and low birth weight neonates, also occurs in the term infant and accounts for 10% of all NEC cases. Despite there being fewer reported cases of NEC in term infants, these presentations demonstrate differences in the onset, severity and risk factors from the classic presentation observed in premature infants. We present a novel case of term NEC that contravenes the reported literature making departures from clinical presentation, risk factors and location of perforation in an otherwise healthy term two-day old infant born after an uncomplicated pregnancy who presented with hematochezia. CASE PRESENTATION: A healthy term baby born after an uneventful pregnancy presented with bloody stool at 2 days of life who was otherwise well. Investigations revealed pneumoperitoneum from a large proximal transverse colonic perforation secondary to NEC. No typical risk factors for NEC were found. CONCLUSION: Given the life-threatening potential of an unrecognized perforation we recommend the inclusion of NEC on the differential for neonatal hematochezia. BioMed Central 2021-01-07 /pmc/articles/PMC7791759/ /pubmed/33413665 http://dx.doi.org/10.1186/s40748-020-00124-0 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Hudson, Jo-Anna
Byrns, Simon
Nizalik, Elizabeth
Ferretti, Emanuela
Case report: necrotizing enterocolitis with a transverse colonic perforation in a 2-day old term neonate and literature review
title Case report: necrotizing enterocolitis with a transverse colonic perforation in a 2-day old term neonate and literature review
title_full Case report: necrotizing enterocolitis with a transverse colonic perforation in a 2-day old term neonate and literature review
title_fullStr Case report: necrotizing enterocolitis with a transverse colonic perforation in a 2-day old term neonate and literature review
title_full_unstemmed Case report: necrotizing enterocolitis with a transverse colonic perforation in a 2-day old term neonate and literature review
title_short Case report: necrotizing enterocolitis with a transverse colonic perforation in a 2-day old term neonate and literature review
title_sort case report: necrotizing enterocolitis with a transverse colonic perforation in a 2-day old term neonate and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791759/
https://www.ncbi.nlm.nih.gov/pubmed/33413665
http://dx.doi.org/10.1186/s40748-020-00124-0
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