Inflammatory M1-like macrophages polarized by NK-4 undergo enhanced phenotypic switching to an anti-inflammatory M2-like phenotype upon co-culture with apoptotic cells

BACKGROUND: NK-4 has been used to promote wound healing since the early-1950s; however, the mechanism of action of NK-4 is unknown. In this study, we examined whether NK-4 exerts a regulatory effect on macrophages, which play multiple roles during wound healing from the initial inflammatory phase un...

Descripción completa

Detalles Bibliográficos
Autores principales: Kohno, Keizo, Koya-Miyata, Satomi, Harashima, Akira, Tsukuda, Takahiko, Katakami, Masataka, Ariyasu, Toshio, Ushio, Shimpei, Iwaki, Kanso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791770/
https://www.ncbi.nlm.nih.gov/pubmed/33413430
http://dx.doi.org/10.1186/s12950-020-00267-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791770/
https://www.ncbi.nlm.nih.gov/pubmed/33413430
http://dx.doi.org/10.1186/s12950-020-00267-z

Ejemplares similares