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N-acetylcysteine dose-dependently improves the analgesic effect of acetaminophen on the rat hot plate test
BACKGROUND: Acetaminophen (APAP) induced hepatotoxicity is a clinically important problem. Up to now, interventive therapy with n-acetylcysteine (NAC) has been considered as a gold-standard treatment for APAP overdose. However, no study has focused on the efficacy of these drugs’ concurrent administ...
Autores principales: | Nakhaee, Samaneh, Dastjerdi, Mohammad, Roumi, Hesam, Mehrpour, Omid, Farrokhfall, Khadijeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791802/ https://www.ncbi.nlm.nih.gov/pubmed/33413696 http://dx.doi.org/10.1186/s40360-020-00469-4 |
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