The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo

BACKGROUND: Rho-family GTPases, including Ras-related C3 botulinum toxin substrate 1 (Rac1) and cell division control protein 42 (Cdc42), are important modulators of cancer-relevant cell functions and are viewed as promising therapeutic targets. Based on high-throughput screening and cheminformatics...

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Detalles Bibliográficos
Autores principales: Grimes, Martha M., Kenney, S. Ray, Dominguez, Dayna R., Brayer, Kathryn J., Guo, Yuna, Wandinger-Ness, Angela, Hudson, Laurie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791840/
https://www.ncbi.nlm.nih.gov/pubmed/33413202
http://dx.doi.org/10.1186/s12885-020-07716-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791840/
https://www.ncbi.nlm.nih.gov/pubmed/33413202
http://dx.doi.org/10.1186/s12885-020-07716-1

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