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Syngeneic homograft of framework regions enhances the affinity of the mouse anti-human epidermal receptor 2 single-chain antibody e23sFv

e23sFv is a HER2-targeted single-chain variable fragment (scFV) that was characterized as the targeting portion of a HER2-targeted tumour proapoptotic molecule in our previous study. In vitro antibody affinity maturation is a method to enhance antibody affinity either by complementarity-determining...

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Detalles Bibliográficos
Autores principales:	Ou-Yang, Qing, Ren, Jun-Lin, Yan, Bo, Feng, Jian-Nan, Yang, An-Gang, Zhao, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791966/ https://www.ncbi.nlm.nih.gov/pubmed/33456503 http://dx.doi.org/10.3892/etm.2020.9568

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