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A novel small molecule CXCR4 antagonist potently mobilizes hematopoietic stem cells in mice and monkeys

BACKGROUND: Hematopoietic stem cell (HSC) transplantation is an effective treatment strategy for many types of diseases. Peripheral blood (PB) is the most commonly used source of bone marrow (BM)-derived stem cells for current HSC transplantation. However, PB usually contains very few HSCs under nor...

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Detalles Bibliográficos
Autores principales:	Fang, Xiao, Fang, Xiong, Mao, Yujia, Ciechanover, Aaron, Xu, Yan, An, Jing, Huang, Ziwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791974/ https://www.ncbi.nlm.nih.gov/pubmed/33413613 http://dx.doi.org/10.1186/s13287-020-02073-z

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