Cargando…

Transcriptomic analysis identifies organ-specific metastasis genes and pathways across different primary sites

BACKGROUND: Metastasis is the most devastating stage of cancer progression and often shows a preference for specific organs. METHODS: To reveal the mechanisms underlying organ-specific metastasis, we systematically analyzed gene expression profiles for three common metastasis sites across all availa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Lin, Fan, Ming, Napolitano, Francesco, Gao, Xin, Xu, Ying, Li, Lihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791985/ https://www.ncbi.nlm.nih.gov/pubmed/33413400 http://dx.doi.org/10.1186/s12967-020-02696-z

Ejemplares similares

Site-specific characterization of endogenous SUMOylation across species and organs
por: Hendriks, Ivo A., et al.
Publicado: (2018)

Identifying metabolomic features that predict metastasis of melanoma from a primary site
por: Shi, Xiaolei, et al.
Publicado: (2014)

Transcriptomic and Network Analysis Identifies Shared and Unique Pathways across Dementia Spectrum Disorders
por: Santiago, Jose A., et al.
Publicado: (2020)

Exosomes and organ-specific metastasis
por: Zhao, Lei, et al.
Publicado: (2021)

FMRP expression in primary breast tumor cells correlates with recurrence and specific site of metastasis
por: Caredda, E., et al.
Publicado: (2023)

Site-Specific Metastasis and Survival in Papillary Thyroid Cancer: The Importance of Brain and Multi-Organ Disease
por: Toraih, Eman A., et al.
Publicado: (2021)

Metastatic pathway-specific transcriptome analysis identifies MFSD4 as a putative tumor suppressor and biomarker for hepatic metastasis in patients with gastric cancer
por: Kanda, Mitsuro, et al.
Publicado: (2016)

Organ-Specific Transcriptome Analysis Identifies Candidate Genes Involved in the Stem Specialization of Bermudagrass (Cynodon dactylon L.)
por: Chen, Si, et al.
Publicado: (2021)

A transcriptome-based approach to identify functional modules within and across primary human immune cells
por: Mola, Saraï, et al.
Publicado: (2020)

Promoter-level transcriptome in primary lesions of endometrial cancer identified biomarkers associated with lymph node metastasis
por: Yoshida, Emiko, et al.
Publicado: (2017)

Comparable prevalence of distant metastasis and survival of different primary site for LN + pancreatic tumor
por: Lou, Xin, et al.
Publicado: (2020)

Organ-Specificity of Breast Cancer Metastasis
por: Ibragimova, Marina K., et al.
Publicado: (2023)

Gene expression profiles of breast cancer metastasis according to organ site
por: Brasó‐Maristany, Fara, et al.
Publicado: (2021)

Pan-organ transcriptome variation across 21 cancer types
por: Hu, Wangxiong, et al.
Publicado: (2016)

Establishment of monoclonal HCC cell lines with organ site-specific tropisms
por: Wan, Jinliang, et al.
Publicado: (2015)

Locally sourced: site-specific immune barriers to metastasis
por: Correia, Ana Luísa
Publicado: (2023)

CD4(+) T Cell‐Specific Proteomic Pathways Identified in Progression of Hypertension Across Postmenopausal Transition
por: Uhlorn, Joshua A., et al.
Publicado: (2021)

Stromal Transcriptional Profiles Reveal Hierarchies of Anatomical Site, Serum Response and Disease and Identify Disease Specific Pathways
por: Filer, Andrew, et al.
Publicado: (2015)

RAMPred: identifying the N(1)-methyladenosine sites in eukaryotic transcriptomes
por: Chen, Wei, et al.
Publicado: (2016)

Extracellular vesicles in the development of organ‐specific metastasis
por: Urabe, Fumihiko, et al.
Publicado: (2021)

Transcriptome-wide and stratified genomic structural equation modeling identify neurobiological pathways shared across diverse cognitive traits
por: Grotzinger, Andrew D., et al.
Publicado: (2022)

Integrated metabolome and transcriptome analysis of Magnolia champaca identifies biosynthetic pathways for floral volatile organic compounds
por: Dhandapani, Savitha, et al.
Publicado: (2017)

Transcriptomic profile comparison reveals conservation of ionocytes across multiple organs
por: Pou Casellas, Carla, et al.
Publicado: (2023)

Mass Spectrometry Amyloid Typing Is Reproducible across Multiple Organ Sites
por: Holub, Dusan, et al.
Publicado: (2019)

Organ-specific cholesterol metabolic aberration fuels liver metastasis of colorectal cancer
por: Zhang, Kai-Li, et al.
Publicado: (2021)

Immunogenomic intertumor heterogeneity across primary and metastatic sites in a patient with lung adenocarcinoma
por: Chen, Runzhe, et al.
Publicado: (2022)

Organ-specific enhancement of metastasis by spontaneous ploidy duplication and cell size enlargement
por: Lu, Xin, et al.
Publicado: (2010)

Tumor-Derived Exosomes Modulate Primary Site Tumor Metastasis
por: Bai, Suwen, et al.
Publicado: (2022)

Abstract 89: Identifying The Myeloid Subpopulation Responsible For Tissue Fibrosis Across Organ Systems Via Machine Learning Parameterization And Predictive Transcriptomics
por: Stepien, David M., et al.
Publicado: (2020)

Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
por: Marie, Kerrie L., et al.
Publicado: (2020)

Site-specific programming of the host epithelial transcriptome by the gut microbiota
por: Sommer, Felix, et al.
Publicado: (2015)

Predicting liver and lung metastasis in esophageal cancer: does the site of primary tumor really matter?
por: Lam, Ka-On, et al.
Publicado: (2020)

Machine Learning for the Prediction of Synchronous Organ-Specific Metastasis in Patients With Lung Cancer
por: Gao, Huan, et al.
Publicado: (2022)

The landscape and driver potential of site-specific hotspots across cancer genomes
por: Juul, Randi Istrup, et al.
Publicado: (2021)

Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
por: Rossini, Daniele, et al.
Publicado: (2013)

Integrated analyses of single-cell transcriptomics identify metastasis-associated myeloid subpopulations in breast cancer lung metastasis
por: Huang, Zhen, et al.
Publicado: (2023)

Genome- and Transcriptome-Wide Association Studies Identify Susceptibility Genes and Pathways for Periodontitis
por: Zhu, Guirong, et al.
Publicado: (2022)

Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease
por: Bandres-Ciga, S., et al.
Publicado: (2020)

The Clinicopathological and Survival Profiles Comparison Across Primary Sites in Acral Melanoma
por: Wei, Xiaoting, et al.
Publicado: (2020)

An evidence-based knowledgebase of metastasis suppressors to identify key pathways relevant to cancer metastasis
por: Zhao, Min, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_0tu4aolooim3ss6i5a0u2hhmr9