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scReQTL: an approach to correlate SNVs to gene expression from individual scRNA-seq datasets

BACKGROUND: Recently, pioneering expression quantitative trait loci (eQTL) studies on single cell RNA sequencing (scRNA-seq) data have revealed new and cell-specific regulatory single nucleotide variants (SNVs). Here, we present an alternative QTL-related approach applicable to transcribed SNV loci...

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Detalles Bibliográficos
Autores principales: Liu, Hongyu, Prashant, N. M., Spurr, Liam F., Bousounis, Pavlos, Alomran, Nawaf, Ibeawuchi, Helen, Sein, Justin, Słowiński, Piotr, Tsaneva-Atanasova, Krasimira, Horvath, Anelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791999/
https://www.ncbi.nlm.nih.gov/pubmed/33419390
http://dx.doi.org/10.1186/s12864-020-07334-y