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Modulation of BRD4 in HIV epigenetic regulation: implications for finding an HIV cure

Following reverse transcription, HIV viral DNA is integrated into host cell genomes and establishes a stable latent infection, which has posed a major obstacle for obtaining a cure for HIV. HIV proviral transcription is regulated in cellular reservoirs by complex host epigenetic and transcriptional...

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Detalles Bibliográficos
Autores principales: Alamer, Edrous, Zhong, Chaojie, Hajnik, Renee, Soong, Lynn, Hu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792063/
https://www.ncbi.nlm.nih.gov/pubmed/33413475
http://dx.doi.org/10.1186/s12977-020-00547-9

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