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Human embryonic stem cell-derived extracellular vesicles alleviate retinal degeneration by upregulating Oct4 to promote retinal Müller cell retrodifferentiation via HSP90

OBJECTIVE: Retinal degenerative diseases remain the dominant causes of blindness worldwide, and cell replacement is viewed as a promising therapeutic direction. However, the resources of seed cells are hard to obtain. To further explore this therapeutic approach, human embryonic stem extracellular v...

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Detalles Bibliográficos
Autores principales: Ke, Yifeng, Fan, Xiaoe, Hao, Rui, Dong, Lijie, Xue, Min, Tan, Liangzhang, Yang, Chunbo, Li, Xiaorong, Ren, Xinjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792097/
https://www.ncbi.nlm.nih.gov/pubmed/33413616
http://dx.doi.org/10.1186/s13287-020-02034-6