GDF-5 promotes epidermal stem cells proliferation via Foxg1-cyclin D1 signaling

OBJECTIVE: Epidermal stem cells (EpSCs) can self-renew, which are responsible for the long-term maintenance of the skin, and it also plays a critical role in wound re-epithelization, but the mechanism underlying EpSCs proliferation is unclear. GDF-5, also known as BMP-14, is a member of the BMP fami...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaohong, Bian, Ruyu, Wang, Fan, Wang, Ying, Li, Xue, Guo, Yicheng, Zhang, Xiaorong, Luo, Gaoxing, Zhan, Rixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792190/
https://www.ncbi.nlm.nih.gov/pubmed/33413682
http://dx.doi.org/10.1186/s13287-020-02106-7

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