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Increased Glucose Availability Attenuates Myocardial Ketone Body Utilization

BACKGROUND: Perturbations in myocardial substrate utilization have been proposed to contribute to the pathogenesis of cardiac dysfunction in diabetic subjects. The failing heart in nondiabetics tends to decrease reliance on fatty acid and glucose oxidation, and increases reliance on ketone body oxid...

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Detalles Bibliográficos
Autores principales: Brahma, Manoja K., Ha, Chae‐Myeong, Pepin, Mark E., Mia, Sobuj, Sun, Zhihuan, Chatham, John C., Habegger, Kirk M., Abel, Evan Dale, Paterson, Andrew J., Young, Martin E., Wende, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792234/
https://www.ncbi.nlm.nih.gov/pubmed/32750298
http://dx.doi.org/10.1161/JAHA.119.013039