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Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma

BACKGROUND: Asthma is a chronic inflammatory disease characterized by airway remodeling and inflammation. Rhynchophylline is a kind of indole alkaloid isolated from Uncaria rhynchophylla. Here we investigated the effect of rhynchophylline on autophagy in asthma. METHODS: A mice model of asthma was e...

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Detalles Bibliográficos
Autores principales:	Li, Hui, Bi, Qianyu, Cui, Hongxia, Lv, Chuanfeng, Wang, Meng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792286/ https://www.ncbi.nlm.nih.gov/pubmed/33413331 http://dx.doi.org/10.1186/s12906-020-03187-w

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