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The Effect of Chronic Mild Stress and Escitalopram on the Expression and Methylation Levels of Genes Involved in the Oxidative and Nitrosative Stresses as Well as Tryptophan Catabolites Pathway in the Blood and Brain Structures
Previous studies suggest that depression may be associated with reactive oxygen species overproduction and disorders of the tryptophan catabolites pathway. Moreover, one-third of patients do not respond to conventional pharmacotherapy. Therefore, the study investigates the molecular effect of escita...
Autores principales: | Wigner, Paulina, Synowiec, Ewelina, Jóźwiak, Paweł, Czarny, Piotr, Bijak, Michał, Białek, Katarzyna, Szemraj, Janusz, Gruca, Piotr, Papp, Mariusz, Śliwiński, Tomasz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792593/ https://www.ncbi.nlm.nih.gov/pubmed/33374959 http://dx.doi.org/10.3390/ijms22010010 |
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