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Pharmacological Inhibition of mTORC2 Reduces Migration and Metastasis in Melanoma

Despite recent advances in therapy, liver metastasis from melanoma is still associated with poor prognosis. Although targeting the mTOR signaling pathway exerts potent anti-tumor activity, little is known about specific mTORC2 inhibition regarding liver metastasis. Using the novel mTORC2 specific in...

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Detalles Bibliográficos
Autores principales:	Guenzle, Jessica, Akasaka, Harue, Joechle, Katharina, Reichardt, Wilfried, Venkatasamy, Aina, Hoeppner, Jens, Hellerbrand, Claus, Fichtner-Feigl, Stefan, Lang, Sven A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792954/ https://www.ncbi.nlm.nih.gov/pubmed/33375117 http://dx.doi.org/10.3390/ijms22010030

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