Extracellular Matrix Composition Modulates the Responsiveness of Differentiated and Stem Pancreatic Cancer Cells to Lipophilic Derivate of Gemcitabine

Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease. Gemcitabine (GEM) is used as the gold standard drug in PDAC treatment. However, due to its poor efficacy, it remains urgent to identify novel strategies to overcome resistance issues. In this context, an intense stroma r...

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Detalles Bibliográficos
Autores principales: Forciniti, Stefania, Dalla Pozza, Elisa, Greco, Maria Raffaella, Amaral Carvalho, Tiago Miguel, Rolando, Barbara, Ambrosini, Giulia, Carmona-Carmona, Cristian Andres, Pacchiana, Raffaella, Di Molfetta, Daria, Donadelli, Massimo, Arpicco, Silvia, Palmieri, Marta, Reshkin, Stephan Joel, Dando, Ilaria, Cardone, Rosa Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792955/
https://www.ncbi.nlm.nih.gov/pubmed/33375106
http://dx.doi.org/10.3390/ijms22010029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792955/
https://www.ncbi.nlm.nih.gov/pubmed/33375106
http://dx.doi.org/10.3390/ijms22010029

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