Cargando…

Role of NMR in High Ordered Structure Characterization of Monoclonal Antibodies

Obtaining high ordered structure (HOS) information is of importance to guarantee the efficacy and safety of monoclonal antibodies (mAbs) in clinical application. Assessment of HOS should ideally be performed in a non-invasive manner under their formulated storage conditions, as any perturbation can...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tokunaga, Yuji, Takeuchi, Koh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793058/ https://www.ncbi.nlm.nih.gov/pubmed/33375207 http://dx.doi.org/10.3390/ijms22010046

Ejemplares similares

Spotlight on the Ballet of Proteins: The Structural Dynamic Properties of Proteins Illuminated by Solution NMR
por: Tokunaga, Yuji, et al.
Publicado: (2020)

Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics
por: Brinson, Robert G., et al.
Publicado: (2018)

Function-Related Dynamics in Multi-Spanning Helical Membrane Proteins Revealed by Solution NMR
por: Takeuchi, Koh, et al.
Publicado: (2021)

Development of antibody arrays for monoclonal antibody Higher Order Structure analysis
por: Wang, Xing, et al.
Publicado: (2013)

2D NMR Analysis as a Sensitive Tool for Evaluating the Higher-Order Structural Integrity of Monoclonal Antibody against COVID-19
por: Cantini, Francesca, et al.
Publicado: (2022)

Biosimilar structural comparability assessment by NMR: from small proteins to monoclonal antibodies
por: Japelj, Boštjan, et al.
Publicado: (2016)

Characterizing monoclonal antibody formulations in arginine glutamate solutions using (1)H NMR spectroscopy
por: Kheddo, Priscilla, et al.
Publicado: (2016)

Analytical Techniques for the Characterization and Quantification of Monoclonal Antibodies
por: Alhazmi, Hassan A., et al.
Publicado: (2023)

Utility of High Resolution 2D NMR Fingerprinting in Assessing Viscosity of Therapeutic Monoclonal Antibodies
por: Majumder, Subhabrata, et al.
Publicado: (2022)

The Role of Monoclonal Antibodies in the Management of Leukemia
por: Al-Ameri, Ali, et al.
Publicado: (2010)

NMR of ordered liquids
por: Burnell, E Elliott, et al.
Publicado: (2010)

Targeting the cryptic sites: NMR-based strategy to improve protein druggability by controlling the conformational equilibrium
por: Mizukoshi, Yumiko, et al.
Publicado: (2020)

The role of NMR in leveraging dynamics and entropy in drug design
por: Dubey, Abhinav, et al.
Publicado: (2020)

Unambiguous identification of α-Gal epitopes in intact monoclonal antibodies by NMR spectroscopy
por: Hinterholzer, Arthur, et al.
Publicado: (2022)

Structural and functional characterization of a monoclonal antibody blocking TIGIT
por: Jeong, Bo-Seong, et al.
Publicado: (2022)

GPCR structural characterization by NMR spectroscopy in solution: GPCR structural characterization by NMR
por: Yang, Lingyun, et al.
Publicado: (2022)

Monoclonal Antibody Therapies for High Risk Neuroblastoma
por: Furman, Wayne L
Publicado: (2021)

The role of IgG subclass of mouse monoclonal antibodies in antibody-dependent enhancement of feline infectious peritonitis virus infection of feline macrophages
por: Hohdatsu, T., et al.
Publicado: (1994)

Structural Characterization of Intrinsically Disordered Proteins by NMR Spectroscopy
por: Kosol, Simone, et al.
Publicado: (2013)

Quantification of natural abundance NMR data differentiates the solution behavior of monoclonal antibodies and their fragments
por: Ban, David, et al.
Publicado: (2021)

The Role of Fc Receptors on the Effectiveness of Therapeutic Monoclonal Antibodies
por: Gogesch, Patricia, et al.
Publicado: (2021)

Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms
por: Bedinger, Daniel, et al.
Publicado: (2015)

Development and Characterization of an Anti-Cancer Monoclonal Antibody for Treatment of Human Carcinomas
por: Tsang, Kwong yok, et al.
Publicado: (2022)

NMR Characterization of Lignans
por: Consonni, Roberto, et al.
Publicado: (2022)

Role of monoclonal antibody drugs in the treatment of COVID-19
por: Ucciferri, Claudio, et al.
Publicado: (2020)

Emerging Role of the Spleen in the Pharmacokinetics of Monoclonal Antibodies, Nanoparticles and Exosomes
por: Cataldi, Mauro, et al.
Publicado: (2017)

Monoclonal antibody production and characterization for the measurement of plasma high density lipoprotein.
por: Lee, S. H., et al.
Publicado: (1996)

Monoclonal Antibodies in Cancer
por: Ghosh, A.K.
Publicado: (1986)

Enhanced immunization techniques to obtain highly specific monoclonal antibodies
por: de Almeida, Rodrigo, et al.
Publicado: (2017)

Microbials for the production of monoclonal antibodies and antibody fragments
por: Spadiut, Oliver, et al.
Publicado: (2014)

Clathrin structure characterized with monoclonal antibodies. II. Identification of in vivo forms of clathrin
Publicado: (1985)

Clathrin structure characterized with monoclonal antibodies. I. Analysis of multiple antigenic sites
Publicado: (1985)

Monolithic Papain-Immobilized Enzyme Reactors for Automated Structural Characterization of Monoclonal Antibodies
por: Rinaldi, Francesca, et al.
Publicado: (2021)

Forbidden Coherence Transfer of (19)F Nuclei to Quantitatively Measure the Dynamics of a CF(3)-Containing Ligand in Receptor-Bound States
por: Tokunaga, Yuji, et al.
Publicado: (2017)

Monoclonal Antibodies in Cancer Therapy
por: Zahavi, David, et al.
Publicado: (2020)

Monoclonal Antibodies and Airway Diseases
por: Lyly, Annina, et al.
Publicado: (2020)

Therapeutic Applications of Monoclonal Antibodies
por: Berger, Mitchell, et al.
Publicado: (2002)

Monoclonal Antibodies as Neurological Therapeutics
por: Gklinos, Panagiotis, et al.
Publicado: (2021)

Monoclonal antibodies for malaria prevention
por: Aleshnick, Maya, et al.
Publicado: (2022)

Pharmacogenetics of anticancer monoclonal antibodies
por: Shek, Dmitrii, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ue10cgitm1eb1pejej8883bfi1