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Deficiency in Tissue Non-Specific Alkaline Phosphatase Leads to Steatohepatitis in Mice Fed a High Fat Diet Similar to That Produced by a Methionine and Choline Deficient Diet
The liver expresses tissue-nonspecific alkaline phosphatase (TNAP), which may participate in the defense against bacterial components, in cell regulation as part of the purinome or in bile secretion, among other roles. We aimed to study the role of TNAP in the development of hepatosteatosis. TNAP(+/...
Autores principales: | Gámez-Belmonte, Reyes, Tena-Garitaonaindia, Mireia, Hernández-Chirlaque, Cristina, Córdova, Samir, Ceacero-Heras, Diego, de Medina, Fermín Sánchez, Martínez-Augustin, Olga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793076/ https://www.ncbi.nlm.nih.gov/pubmed/33374541 http://dx.doi.org/10.3390/ijms22010051 |
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