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Extended Interactions between HIV-1 Viral RNA and tRNA(Lys3) Are Important to Maintain Viral RNA Integrity

The reverse transcription of the human immunodeficiency virus 1 (HIV-1) initiates upon annealing of the 3′-18-nt of tRNA(Lys3) onto the primer binding site (PBS) in viral RNA (vRNA). Additional intermolecular interactions between tRNA(Lys3) and vRNA have been reported, but their functions remain unc...

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Detalles Bibliográficos
Autores principales:	Gremminger, Thomas, Song, Zhenwei, Ji, Juan, Foster, Avery, Weng, Kexin, Heng, Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793103/ https://www.ncbi.nlm.nih.gov/pubmed/33374603 http://dx.doi.org/10.3390/ijms22010058

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