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A Paradigm Revolution or Just Better Resolution—Will Newly Emerging Superresolution Techniques Identify Chromatin Architecture as a Key Factor in Radiation-Induced DNA Damage and Repair Regulation?
SIMPLE SUMMARY: Radiation-induced double-strand breaks (DSBs) are the most toxic and most difficult to repair DNA lesions and are very heterogeneous. These characteristics place considerable demands on the selection of the most suitable repair mechanism at each individual damage site. Here, we revie...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793109/ https://www.ncbi.nlm.nih.gov/pubmed/33374540 http://dx.doi.org/10.3390/cancers13010018 |