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Bile Acid Conjugates with Anticancer Activity: Most Recent Research

The advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological prop...

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Detalles Bibliográficos
Autores principales: Navacchia, Maria Luisa, Marchesi, Elena, Perrone, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793148/
https://www.ncbi.nlm.nih.gov/pubmed/33374573
http://dx.doi.org/10.3390/molecules26010025
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author Navacchia, Maria Luisa
Marchesi, Elena
Perrone, Daniela
author_facet Navacchia, Maria Luisa
Marchesi, Elena
Perrone, Daniela
author_sort Navacchia, Maria Luisa
collection PubMed
description The advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological properties, as well as their different chemical/biochemical reactive moieties, bile acids can be considered very interesting starting molecules for conjugation with natural or synthetic bioactive molecules.
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spelling pubmed-77931482021-01-09 Bile Acid Conjugates with Anticancer Activity: Most Recent Research Navacchia, Maria Luisa Marchesi, Elena Perrone, Daniela Molecules Review The advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological properties, as well as their different chemical/biochemical reactive moieties, bile acids can be considered very interesting starting molecules for conjugation with natural or synthetic bioactive molecules. MDPI 2020-12-23 /pmc/articles/PMC7793148/ /pubmed/33374573 http://dx.doi.org/10.3390/molecules26010025 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Navacchia, Maria Luisa
Marchesi, Elena
Perrone, Daniela
Bile Acid Conjugates with Anticancer Activity: Most Recent Research
title Bile Acid Conjugates with Anticancer Activity: Most Recent Research
title_full Bile Acid Conjugates with Anticancer Activity: Most Recent Research
title_fullStr Bile Acid Conjugates with Anticancer Activity: Most Recent Research
title_full_unstemmed Bile Acid Conjugates with Anticancer Activity: Most Recent Research
title_short Bile Acid Conjugates with Anticancer Activity: Most Recent Research
title_sort bile acid conjugates with anticancer activity: most recent research
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793148/
https://www.ncbi.nlm.nih.gov/pubmed/33374573
http://dx.doi.org/10.3390/molecules26010025
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AT marchesielena bileacidconjugateswithanticanceractivitymostrecentresearch
AT perronedaniela bileacidconjugateswithanticanceractivitymostrecentresearch