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Bile Acid Conjugates with Anticancer Activity: Most Recent Research
The advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological prop...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793148/ https://www.ncbi.nlm.nih.gov/pubmed/33374573 http://dx.doi.org/10.3390/molecules26010025 |
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author | Navacchia, Maria Luisa Marchesi, Elena Perrone, Daniela |
author_facet | Navacchia, Maria Luisa Marchesi, Elena Perrone, Daniela |
author_sort | Navacchia, Maria Luisa |
collection | PubMed |
description | The advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological properties, as well as their different chemical/biochemical reactive moieties, bile acids can be considered very interesting starting molecules for conjugation with natural or synthetic bioactive molecules. |
format | Online Article Text |
id | pubmed-7793148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77931482021-01-09 Bile Acid Conjugates with Anticancer Activity: Most Recent Research Navacchia, Maria Luisa Marchesi, Elena Perrone, Daniela Molecules Review The advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological properties, as well as their different chemical/biochemical reactive moieties, bile acids can be considered very interesting starting molecules for conjugation with natural or synthetic bioactive molecules. MDPI 2020-12-23 /pmc/articles/PMC7793148/ /pubmed/33374573 http://dx.doi.org/10.3390/molecules26010025 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Navacchia, Maria Luisa Marchesi, Elena Perrone, Daniela Bile Acid Conjugates with Anticancer Activity: Most Recent Research |
title | Bile Acid Conjugates with Anticancer Activity: Most Recent Research |
title_full | Bile Acid Conjugates with Anticancer Activity: Most Recent Research |
title_fullStr | Bile Acid Conjugates with Anticancer Activity: Most Recent Research |
title_full_unstemmed | Bile Acid Conjugates with Anticancer Activity: Most Recent Research |
title_short | Bile Acid Conjugates with Anticancer Activity: Most Recent Research |
title_sort | bile acid conjugates with anticancer activity: most recent research |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793148/ https://www.ncbi.nlm.nih.gov/pubmed/33374573 http://dx.doi.org/10.3390/molecules26010025 |
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