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Multiobjective optimization identifies cancer-selective combination therapies

Combinatorial therapies are required to treat patients with advanced cancers that have become resistant to monotherapies through rewiring of redundant pathways. Due to a massive number of potential drug combinations, there is a need for systematic approaches to identify safe and effective combinatio...

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Detalles Bibliográficos
Autores principales: Pulkkinen, Otto I., Gautam, Prson, Mustonen, Ville, Aittokallio, Tero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793282/
https://www.ncbi.nlm.nih.gov/pubmed/33370253
http://dx.doi.org/10.1371/journal.pcbi.1008538

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