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Evaluation of CD8 T cell killing models with computer simulations of 2-photon imaging experiments
In vivo imaging of cytotoxic T lymphocyte (CTL) killing activity revealed that infected cells have a higher observed probability of dying after multiple contacts with CTLs. We developed a three-dimensional agent-based model to discriminate different hypotheses about how infected cells get killed bas...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793284/ https://www.ncbi.nlm.nih.gov/pubmed/33370254 http://dx.doi.org/10.1371/journal.pcbi.1008428 |