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Genomic analysis of mutations in platelet mitochondria in a case of benzene-induced leukaemia: A case report
INTRODUCTION: As a hematopoietic carcinogen, benzene induces human leukemia through its active metabolites such as benzoquinone, which may cause oxidative damage to cancer-related nuclear genes by increasing reactive oxygen species (ROS). Mitochondrion is the main regulatory organelle of ROS, geneti...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793417/ https://www.ncbi.nlm.nih.gov/pubmed/33429764 http://dx.doi.org/10.1097/MD.0000000000024014 |