Pathogenic Impacts of Dysregulated Polycomb Repressive Complex Function in Hematological Malignancies

Polycomb repressive complexes (PRCs) are epigenetic regulators that mediate repressive histone modifications. PRCs play a pivotal role in the maintenance of hematopoietic stem cells through repression of target genes involved in cell proliferation and differentiation. Next-generation sequencing tech...

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Detalles Bibliográficos
Autores principales: Kaito, Satoshi, Iwama, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793497/
https://www.ncbi.nlm.nih.gov/pubmed/33374737
http://dx.doi.org/10.3390/ijms22010074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793497/
https://www.ncbi.nlm.nih.gov/pubmed/33374737
http://dx.doi.org/10.3390/ijms22010074

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