Cargando…

Pathogenic Impacts of Dysregulated Polycomb Repressive Complex Function in Hematological Malignancies

Polycomb repressive complexes (PRCs) are epigenetic regulators that mediate repressive histone modifications. PRCs play a pivotal role in the maintenance of hematopoietic stem cells through repression of target genes involved in cell proliferation and differentiation. Next-generation sequencing tech...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaito, Satoshi, Iwama, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793497/ https://www.ncbi.nlm.nih.gov/pubmed/33374737 http://dx.doi.org/10.3390/ijms22010074

Ejemplares similares

The Role of Polycomb Repressive Complex in Malignant Peripheral Nerve Sheath Tumor
por: Zhang, Xiyuan, et al.
Publicado: (2020)

Molecular architecture of polycomb repressive complexes
por: Chittock, Emily C., et al.
Publicado: (2017)

Akt inhibition synergizes with polycomb repressive complex 2 inhibition in the treatment of multiple myeloma
por: Rizk, Mohamed, et al.
Publicado: (2019)

Evolutionary adaptation of the Polycomb repressive complex 2
por: Fischer, Sabrina, et al.
Publicado: (2022)

Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
por: Nakajima-Takagi, Yaeko, et al.
Publicado: (2023)

Polycomb Repressive Complex 2 in Eukaryotes—An Evolutionary Perspective
por: Vijayanathan, Mallika, et al.
Publicado: (2022)

Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer
por: Dong, Guan-Jun, et al.
Publicado: (2022)

A Novel Zinc Finger Protein Zfp277 Mediates Transcriptional Repression of the Ink4a/Arf Locus through Polycomb Repressive Complex 1
por: Negishi, Masamitsu, et al.
Publicado: (2010)

Polycomb Repressive Complex(es) and Their Role in Adult Stem Cells
por: Flora, Pooja, et al.
Publicado: (2021)

Polycomb complexes in normal and malignant hematopoiesis
por: Di Carlo, Valerio, et al.
Publicado: (2019)

Huntingtin facilitates polycomb repressive complex 2
por: Seong, Ihn Sik, et al.
Publicado: (2010)

The structure of Polycomb-repressed chromatin in the bithorax complex
por: Bowman, Sarah K, et al.
Publicado: (2013)

Molecular Regulation of the Polycomb Repressive-Deubiquitinase
por: Reddington, Cameron J., et al.
Publicado: (2020)

Super-Enhancers Dysregulations in Hematological Malignancies
por: Belloucif, Yannis, et al.
Publicado: (2022)

Post-Embryonic Phase Transitions Mediated by Polycomb Repressive Complexes in Plants
por: Hinsch, Valerie, et al.
Publicado: (2021)

The Importance of Networking: Plant Polycomb Repressive Complex 2 and Its Interactors
por: Godwin, James, et al.
Publicado: (2022)

Dysregulated Polycomb Repressive Complex 2 contributes to chronic obstructive pulmonary disease by rewiring stem cell fate
por: Byrd, Aria L., et al.
Publicado: (2022)

Structure and Function of the Polycomb Repressive Complexes PRC1 and PRC2
por: Angrand, Pierre-Olivier
Publicado: (2022)

Polycomb repressive complex’s evolutionary conserved function: the role of EZH2 status and cellular background
por: Gall Trošelj, Koraljka, et al.
Publicado: (2016)

Promiscuous RNA binding by Polycomb Repressive Complex 2
por: Davidovich, Chen, et al.
Publicado: (2013)

Molecular architecture of human polycomb repressive complex 2
por: Ciferri, Claudio, et al.
Publicado: (2012)

Polycomb repressive complex 1 controls uterine decidualization
por: Bian, Fenghua, et al.
Publicado: (2016)

The molecular principles of gene regulation by Polycomb repressive complexes
por: Blackledge, Neil P., et al.
Publicado: (2021)

The ACF chromatin-remodeling complex is essential for Polycomb repression
por: Wiles, Elizabeth T, et al.
Publicado: (2022)

Polycomb Recruiters Inside and Outside of the Repressed Domains
por: Erokhin, Maksim, et al.
Publicado: (2023)

Polycomb Repressive Complex 2 and KRYPTONITE regulate pathogen-induced programmed cell death in Arabidopsis
por: Dvořák Tomaštíková, Eva, et al.
Publicado: (2021)

Enhancer of Polycomb and the Tip60 complex repress hematological tumor initiation by negatively regulating JAK/STAT pathway activity
por: Bailetti, Alessandro A., et al.
Publicado: (2019)

Role of Polycomb Complexes in Normal and Malignant Plasma Cells
por: Varlet, Emmanuel, et al.
Publicado: (2020)

Possible roles for polycomb repressive complex 2 in cereal endosperm
por: Tonosaki, Kaoru, et al.
Publicado: (2015)

LATS2 Positively Regulates Polycomb Repressive Complex 2
por: Torigata, Kosuke, et al.
Publicado: (2016)

Polycomb repressive complex 1 modifies transcription of active genes
por: Pherson, Michelle, et al.
Publicado: (2017)

De Novo Polycomb Recruitment and Repressive Domain Formation
por: Hernández-Romero, Itzel Alejandra, et al.
Publicado: (2022)

The Contribution of the Zebrafish Model to the Understanding of Polycomb Repression in Vertebrates
por: Hanot, Mariette, et al.
Publicado: (2023)

Polycomb Repressive Complex 2 is essential for development and maintenance of a functional TEC compartment
por: Singarapu, Nandini, et al.
Publicado: (2018)

Repression of FLOWERING LOCUS C and FLOWERING LOCUS T by the Arabidopsis Polycomb Repressive Complex 2 Components
por: Jiang, Danhua, et al.
Publicado: (2008)

Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression
por: Bar, Carmit, et al.
Publicado: (2019)

The role and mechanisms of polycomb repressive complex 2 on the regulation of osteogenic and neurogenic differentiation of stem cells
por: Cao, Yangyang, et al.
Publicado: (2021)

The Polycomb Repressive Complex 2 Is a Potential Target of SUMO Modifications
por: Riising, Eva Madi, et al.
Publicado: (2008)

Polycomb Repressive Complex 2 Controls the Embryo-to-Seedling Phase Transition
por: Bouyer, Daniel, et al.
Publicado: (2011)

EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells
por: Ragazzini, Roberta, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4qc82raopjmk6d3qb4tvq1j00b