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A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival in tuberculous meningitis
Tuberculous meningitis has high mortality, linked to excessive inflammation. However, adjunctive anti-inflammatory corticosteroids reduce mortality by only 30%, suggesting that inflammatory pathophysiology causes only a subset of deaths. In Vietnam, the survival benefit of anti-inflammatory corticos...
Autores principales: | Whitworth, Laura, Coxon, Jacob, van Laarhoven, Arjan, Thuong, Nguyen Thuy Thuong, Dian, Sofiati, Alisjahbana, Bachti, Ganiem, Ahmad Rizal, van Crevel, Reinout, Thwaites, Guy E, Troll, Mark, Edelstein, Paul H, Sewell, Roger, Ramakrishnan, Lalita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793626/ https://www.ncbi.nlm.nih.gov/pubmed/33416499 http://dx.doi.org/10.7554/eLife.61722 |
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