Cargando…

Acute Hyperglycemia May Induce Renal Tubular Injury Through Mitophagy Inhibition

AIM: Acute hyperglycemia is closely related to kidney injury. Oxidative stress activation and notable mitochondria damages were found under acute hyperglycemia treatment in our previous work. In the present study, we explored the dose-effect relationship and the pivotal role of mitophagy in acute hy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jingyu, Yue, Xiaodan, Meng, Cheng, Wang, Ziyan, Jin, Xiaofang, Cui, Xiao, Yang, Juhong, Shan, Chunyan, Gao, Zhongai, Yang, Yanhui, Li, Jing, Chang, Bai, Chang, Baocheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793649/ https://www.ncbi.nlm.nih.gov/pubmed/33424763 http://dx.doi.org/10.3389/fendo.2020.536213

Ejemplares similares

Hyperinsulinemia impairs the metabolic switch to ketone body utilization in proximal renal tubular epithelial cells under energy crisis via the inhibition of the SIRT3/SMCT1 pathway
por: Xie, Jinlan, et al.
Publicado: (2022)

Pathological Hyperinsulinemia and Hyperglycemia in the Impaired Glucose Tolerance Stage Mediate Endothelial Dysfunction Through miR-21, PTEN/AKT/eNOS, and MARK/ET-1 Pathways
por: Liu, Ran, et al.
Publicado: (2021)

Beta-Hydroxybutyric Acid Inhibits Renal Tubular Reabsorption via the AKT/DAB2/Megalin Signalling Pathway
por: Zuo, Minxia, et al.
Publicado: (2022)

Establishment and validation of the cut-off values of estimated glomerular filtration rate and urinary albumin-to-creatinine ratio for diabetic kidney disease: A multi-center, prospective cohort study
por: Gao, Zhongai, et al.
Publicado: (2022)

Editorial: Rising stars in renal endocrinology: 2021
por: Yang, Juhong, et al.
Publicado: (2023)

Preventive Role of Salsalate in Diabetes Is Associated With Reducing Intestinal Inflammation Through Improvement of Gut Dysbiosis in ZDF Rats
por: Zhang, Xinrong, et al.
Publicado: (2020)

Evaluation of urinary biomarkers for prediction of diabetic kidney disease: a propensity score matching analysis
por: Qin, Yongzhang, et al.
Publicado: (2019)

Hyperinsulinemia contributes to impaired-glucose-tolerance-induced renal injury via mir-7977/SIRT3 signaling
por: Gao, Zhongai, et al.
Publicado: (2020)

Berberine Slows the Progression of Prediabetes to Diabetes in Zucker Diabetic Fatty Rats by Enhancing Intestinal Secretion of Glucagon-Like Peptide-2 and Improving the Gut Microbiota
por: Wang, Ying, et al.
Publicado: (2021)

Bone Marrow-Derived Mesenchymal Stem Cells Ameliorate Sepsis-Induced Acute Kidney Injury by Promoting Mitophagy of Renal Tubular Epithelial Cells via the SIRT1/Parkin Axis
por: Guo, Jun, et al.
Publicado: (2021)

Sex-specific mediating effect of gestational weight gain between pre-pregnancy body mass index and gestational diabetes mellitus
por: Zhang, Shuang, et al.
Publicado: (2022)

Melatonin alleviates renal injury by activating mitophagy in diabetic nephropathy
por: Tang, Hanfen, et al.
Publicado: (2022)

Renal impairment markers in type 2 diabetes patients with different types of hyperuricemia
por: Gao, Zhongai, et al.
Publicado: (2018)

Cellular senescence of renal tubular epithelial cells in renal fibrosis
por: Zhang, Jun-Qing, et al.
Publicado: (2023)

Exenatide Attenuates Obesity-Induced Mitochondrial Dysfunction by Activating SIRT1 in Renal Tubular Cells
por: Wang, Yao, et al.
Publicado: (2021)

Dapagliflozin Attenuates Hyperglycemia Related Osteoporosis in ZDF Rats by Alleviating Hypercalciuria
por: Wang, Ji-Yu, et al.
Publicado: (2019)

Endoplasmic Reticulum Stress Mediates Renal Tubular Vacuolation in BK Polyomavirus-Associated Nephropathy
por: Zhao, Guo-Dong, et al.
Publicado: (2022)

Research progress on extracellular vesicles in the renal tubular injury of diabetic kidney disease
por: Li, Shengjie, et al.
Publicado: (2023)

Atorvastatin inhibits insulin synthesis by inhibiting the Ras/Raf/ERK/CREB pathway in INS-1 cells
por: Sun, Hongxi, et al.
Publicado: (2016)

Corrigendum: Dapagliflozin Attenuates Hyperglycemia Related Osteoporosis in ZDF Rats by Alleviating Hypercalciuria
por: Wang, Ji-Yu, et al.
Publicado: (2020)

Association between hyperglycemia and adverse clinical outcomes of sepsis patients with diabetes
por: Lin, Shan, et al.
Publicado: (2023)

Hyperinsulinemia Can Cause Kidney Disease in the IGT Stage of OLETF Rats via the INS/IRS-1/PI3-K/Akt Signaling Pathway
por: Zhang, Yi, et al.
Publicado: (2019)

Identification of ULK1 as a novel mitophagy-related gene in diabetic nephropathy
por: Yang, Yuan-Yuan, et al.
Publicado: (2023)

Current Challenges and Future Perspectives of Renal Tubular Dysfunction in Diabetic Kidney Disease
por: Duan, Suyan, et al.
Publicado: (2021)

Transcriptomic signatures responding to PKM2 activator TEPP-46 in the hyperglycemic human renal proximal epithelial tubular cells
por: Wang, Zhimin, et al.
Publicado: (2022)

An Intermediary Role of Adenine Nucleotides on Free Fatty Acids-Induced Hyperglycemia in Obese Mice
por: Yang, Xiao, et al.
Publicado: (2019)

Association Between Maternal Hyperglycemia and Composite Maternal-Birth Outcomes
por: Shen, Song-Ying, et al.
Publicado: (2018)

The Hyperglycemia and Hyperketonemia Impaired Bone Microstructures: A Pilot Study in Rats
por: Liu, Qi, et al.
Publicado: (2020)

TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease
por: Wang, Youliang, et al.
Publicado: (2019)

Hyperglycemia Is Not Associated With Higher Volumetric BMD in a Chinese Health Check-up Cohort
por: Wang, Ling, et al.
Publicado: (2022)

The prognosis of patients with postoperative hyperglycemia after Stanford type A aortic dissection surgery and construction of prediction model for postoperative hyperglycemia
por: Chen, Yubin, et al.
Publicado: (2023)

Trends in hospitalizations and emergency department visits among women with hyperglycemia in pregnancy between 2008 and 2017 in Taiwan
por: Wang, Jun-Sing, et al.
Publicado: (2022)

Unusual Presentation of Polyautoimmunity and Renal Tubular Acidosis in an Adolescent With Hashimoto's Thyroiditis and Central Pontine Myelinolysis
por: Bruns, Nora, et al.
Publicado: (2020)

Hyperglycemia and Physical Impairment in Frail Hypertensive Older Adults
por: Pansini, Antonella, et al.
Publicado: (2022)

Osteogenesis of bone marrow mesenchymal stem cell in hyperglycemia
por: Luo, Meng, et al.
Publicado: (2023)

Trends in epidemiology of hyperglycemia in pregnancy in Taiwan, 2008-2017
por: Lin, Shin-Yu, et al.
Publicado: (2023)

Association between sex steroid hormones and subsequent hyperglycemia during pregnancy
por: Meng, Ying, et al.
Publicado: (2023)

Upregulation of TIPE1 in tubular epithelial cell aggravates diabetic nephropathy by disrupting PHB2 mediated mitophagy
por: Liu, Lei, et al.
Publicado: (2022)

Ferroptosis Enhanced Diabetic Renal Tubular Injury via HIF-1α/HO-1 Pathway in db/db Mice
por: Feng, Xiaomeng, et al.
Publicado: (2021)

Vildagliptin Attenuates Myocardial Dysfunction and Restores Autophagy via miR-21/SPRY1/ERK in Diabetic Mice Heart
por: Li, Xiaochen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jgacema29v81ec51rsqhnnd2d7