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Cancer Omics in Africa: Present and Prospects
During the last century, cancer biology has been arguably one of the most investigated research fields. To gain deeper insight into cancer mechanisms, scientists have been attempting to integrate multi omics data in cancer research. Cancer genomics, transcriptomics, metabolomics, proteomics, and meta...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793679/ https://www.ncbi.nlm.nih.gov/pubmed/33425763 http://dx.doi.org/10.3389/fonc.2020.606428 |
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author | El Jaddaoui, Islam Allali, Imane Sehli, Sofia Ouldim, Karim Hamdi, Salsabil Al Idrissi, Najib Nejjari, Chakib Amzazi, Saaïd Bakri, Youssef Ghazal, Hassan |
author_facet | El Jaddaoui, Islam Allali, Imane Sehli, Sofia Ouldim, Karim Hamdi, Salsabil Al Idrissi, Najib Nejjari, Chakib Amzazi, Saaïd Bakri, Youssef Ghazal, Hassan |
author_sort | El Jaddaoui, Islam |
collection | PubMed |
description | During the last century, cancer biology has been arguably one of the most investigated research fields. To gain deeper insight into cancer mechanisms, scientists have been attempting to integrate multi omics data in cancer research. Cancer genomics, transcriptomics, metabolomics, proteomics, and metagenomics are the main multi omics strategies used currently in the diagnosis, prognosis, treatment, and biomarker discovery in cancer. In this review, we describe the use of different multi omics strategies in cancer research in the African continent and discuss the main challenges facing the implementation of these approaches in African countries such as the lack of training programs in bioinformatics in general and omics strategies in particular and suggest paths to address deficiencies. As a way forward, we advocate for the establishment of an “African Cancer Genomics Consortium” to promote intracontinental collaborative projects and enhance engagement in research activities that address indigenous aspects for cancer precision medicine. |
format | Online Article Text |
id | pubmed-7793679 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77936792021-01-09 Cancer Omics in Africa: Present and Prospects El Jaddaoui, Islam Allali, Imane Sehli, Sofia Ouldim, Karim Hamdi, Salsabil Al Idrissi, Najib Nejjari, Chakib Amzazi, Saaïd Bakri, Youssef Ghazal, Hassan Front Oncol Oncology During the last century, cancer biology has been arguably one of the most investigated research fields. To gain deeper insight into cancer mechanisms, scientists have been attempting to integrate multi omics data in cancer research. Cancer genomics, transcriptomics, metabolomics, proteomics, and metagenomics are the main multi omics strategies used currently in the diagnosis, prognosis, treatment, and biomarker discovery in cancer. In this review, we describe the use of different multi omics strategies in cancer research in the African continent and discuss the main challenges facing the implementation of these approaches in African countries such as the lack of training programs in bioinformatics in general and omics strategies in particular and suggest paths to address deficiencies. As a way forward, we advocate for the establishment of an “African Cancer Genomics Consortium” to promote intracontinental collaborative projects and enhance engagement in research activities that address indigenous aspects for cancer precision medicine. Frontiers Media S.A. 2020-12-14 /pmc/articles/PMC7793679/ /pubmed/33425763 http://dx.doi.org/10.3389/fonc.2020.606428 Text en Copyright © 2020 El Jaddaoui, Allali, Sehli, Ouldim, Hamdi, Al Idrissi, Nejjari, Amzazi, Bakri and Ghazal http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology El Jaddaoui, Islam Allali, Imane Sehli, Sofia Ouldim, Karim Hamdi, Salsabil Al Idrissi, Najib Nejjari, Chakib Amzazi, Saaïd Bakri, Youssef Ghazal, Hassan Cancer Omics in Africa: Present and Prospects |
title | Cancer Omics in Africa: Present and Prospects |
title_full | Cancer Omics in Africa: Present and Prospects |
title_fullStr | Cancer Omics in Africa: Present and Prospects |
title_full_unstemmed | Cancer Omics in Africa: Present and Prospects |
title_short | Cancer Omics in Africa: Present and Prospects |
title_sort | cancer omics in africa: present and prospects |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793679/ https://www.ncbi.nlm.nih.gov/pubmed/33425763 http://dx.doi.org/10.3389/fonc.2020.606428 |
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